Caister Academic Press

MRSA: Current Perspectives

Publisher: Caister Academic Press
Edited by: Ad C. Fluit and Franz-Josef Schmitz
Eijkman-Winkler Institute, University Medical Center, Utrecht, The Netherlands
Pages: viii + 340
Publication date: September 2003
ISBN: 978-0-9542464-5-7
Price: GB £219 or US $250Buy book
Publication date: September 2003
ISBN: 978-1-913652-45-6
Price: US $319Buy ebook
MRSA book
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Since their discovery in the 1960s, methicillin-resistant S. aureus (MRSA) strains continue to present unique challenges to clinicians, microbiologists, and the molecular biologists around the world. These organisms are typically resistant to several other antimicrobial agents, including aminoglycosides, chloramphenicol, clindamycin, fluoroquinolones and macrolides and are susceptible only to vancomycin. In fact there is increasing evidence that this susceptibility will soon disappear.

In this book, internationally renown authors comprehensively review all aspects of MRSA research. Topics covered include strategies for the detection and typing of MRSA strains, epidemiological characterisation, molecular evolution of MRSA, vancomycin resistant S. aureus, mechanisms of methicillin resistance, virulence mechanisms in MRSA pathogenesis, recommended treatment of MRSA infections and options for the prevention and control of MRSA infections.

An essential text for all scientists and clinicians with an interest in the Staphylococcus aureus or antibiotic resistance.


"I would happily recommend this text for final year medical and biomedical students, and also recently qualified medical doctors. It is also an excellent text for those with a specific interest in the area, and would be a welcome addition to any medical library's shelves. ... This book contains a plethora of information on a variety of MRSA related subjects ... MRSA: Current Perspectives serves as an excellent knowledge base from which the many areas can be explored at greater depth." from The Biochemist March (2004).

"I highly recommend that you read (this book).... a state-of-the-art study ... interesting reading for microbiologists, molecular biologists, and clinicians." from International Microbiology (2004) 7: 79.

"... a timely and comprehensive monograph bringing together important information which can be read and understood at a basic or advanced level." from Microbiology Today (2004) 31: 98.

"... discussed in a refreshingly broad context." from CAB International (2004).

Table of contents
1. Introduction
Barry D. Cookson, Franz-Josef Schmitz, and Ad C. Fluit
2. Detection of MRSA
Derek Brown and Barry D. Cookson
3. Mechanisms of Methicillin Resistance
Susanne Rohrer, Markus Bischoff, Jutta Rossi, and Brigitte Berger-Bächi
4. MRSA Resistance Mechanisms and Surveillance Data for Non-betalactams and Non-glycopeptides
Ian Morrissey and David J. Farrell
5. Molecular Approaches for the Epidemiological Characterization of Staphylococcus aureus strains
Willem B. van Leeuwen
6. The Molecular Evolution of Methicillin-Resistant Staphylococcus aureus
J. Ross Fitzgerald and James M. Musser
7. Population Structure of MRSA
Ad C. Fluit and Franz-Josef Schmitz
8. Vancomycin-Resistant Staphylococcus aureus
Longzhu Cui and Keiichi Hiramatsu
9. Virulence Mechanisms in MRSA Pathogenesis
Jesse S. Wright III and Richard P. Novick
10. Small Colony Variants - Another Mechanism by Which Staphylococcus aureus Can Evade the Immune response and Antimicrobial Therapy
Christof von Eiff, and Karsten Becker
11. Treatment of MRSA Infections
Debby Ben-David and Ethan Rubinstein
12. Prevention and Control of Methicillin-Resistant Staphylococcus aureus (MRSA)
Uwe Frank
13. Concluding Remarks
Ad C. Fluit and Franz-Josef Schmitz

How to buy this book

(EAN: 9780954246457 9781913652456 Subjects: [bacteriology] [microbiology] [medical microbiology] [molecular microbiology] )