Caister Academic Press

Structural Studies of U-insertion/deletion RNA Editing in Trypanosomes

Blaine H. M. Mooers
from: RNA Editing: Current Research and Future Trends (Edited by: Stefan Maas). Caister Academic Press, U.K. (2013)


We review the progress in the past decade in structural studies of the proteins and RNAs associated with the U-insertion/deletion RNA editing (or k-RNA editing) in the mitochondrion of trypanosomes. This review includes the electron microscopy studies of RNA editing complexes. Beyond the intellectual quest to understand the structural basis of RNA editing, these studies share the goal of using structures of essential proteins to design better inhibitors of RNA editing for medical and research purposes read more ...
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