Rosemary Ann Dorrington and James Roswell Short
from: Insect Virology (Edited by: Sassan Asgari and Karyn N. Johnson). Caister Academic Press, U.K. (2010)
The Tetraviridae are a relatively unknown family of small RNA viruses that exclusively infect the larvae of lepidopteron insect species, many of which are important agricultural pests. While the structure of tetraviral capsids has been well studied, little is known about their biology and the interactions between virus and host that determine their unusually narrow host range and tissue tropism. This is because of the problems associated with developing suitable experimental systems for studying their biology in vivo. This chapter will review recent advances in the understanding of the biology of tetraviruses, highlighting new information on the function and expression of viral translation products and the development of biological systems for elucidating the molecular mechanisms of infection and viral replication read more ...