Flavivirus Fitness and Transmission
Gregory D. Ebel and Laura D. Kramer
from: Molecular Virology and Control of Flaviviruses (Edited by: Pei-Yong Shi). Caister Academic Press, U.K. (2012)
Flavivirus fitness is inextricably linked to the ability of a particular agent to be efficiently transmitted among relevant hosts in natural transmission cycles. Thus, fitness is an inherent component of the virus-host relationship. The mechanisms through which virus fitness is maximized are poorly understood, but have recently been examined in increasing detail. This chapter examines recent developments in the study of flavivirus fitness from both observational and experimental studies, highlighting important emergent and/or resurgent tick- and mosquito-borne members of the flavivirus genus read more ...