Production of Biobutanol, from ABE to Syngas Fermentation
Michael Köpke, Ryan E. Hill, Rasmus O. Jensen and Peter Düerre
from: Biofuels: From Microbes to Molecules (Edited by: Xuefeng Lu). Caister Academic Press, U.K. (2014)
Butanol is an important commodity chemical and due to its properties considered to represent an ideal advanced biofuel. In recent years, in addition to petrochemical production of butanol, fermentation as a means of biobutanol production has been revived. This so called ABE fermentation is not a novel process, and has already been employed commercially for most of the first half of the 20th century. While most of the principles are the same, the rise of genetic tools and metabolic engineering allowed optimization of this process. Through synthetic biology, industrial workhorses as E. coli and yeast have been successfully modified for production of n-butanol, and through a non-fermentative pathway also for production of iso-butanol, a process that is currently commercialized. While all these approaches rely on use of sugar or starch, alternative processes have been developed for sustainable production of biobutanol from CO2 and light with cyanobacteria or by fermenting syngas using acetogens read more ...