Metabolic Engineering: Key for Improving Biological Hydrogen Production
Dipankar Ghosh and Patrick C. Hallenbeck
from: Biofuels: From Microbes to Molecules (Edited by: Xuefeng Lu). Caister Academic Press, U.K. (2014)
Hydrogen is a renewable, efficient and clean fuel. Photobiological and fermentative microorganisms hold great promise as a means for biological hydrogen production. Different metabolic pathways come into play for hydrogen evolution in various microbes depending upon the available substrate, enzyme activity, environmental conditions and growth kinetics of the microbial system. Known microbial systems are unable to achieve the theoretical maximal for either molar hydrogen yield or cumulative or specific hydrogen productivity. The major reasons for this are thermodynamic and physiological barriers related to the metabolisms of the different microorganisms. Here we review the development of metabolically engineered microorganisms for improved biohydrogen production read more ...