Caister Academic Press

Practical Issues in Setting Up and Maintaining a Collection of Therapeutic Bacteriophages: the Finnish Experience

Saija Kiljunen, Jussi Tervonen and Mikael Skurnik
from: Bacterial Viruses: Exploitation for Biocontrol and Therapeutics (Edited by: Aidan Coffey and Colin Buttimer). Caister Academic Press, U.K. (2020) Pages: 645-662.

Abstract

As part of our efforts to make bacteriophage (phage) therapy available to Finnish clinicians to treat patients suffering from infections caused by multi-drug resistant (MDR) bacterial pathogens, we have started a continually growing collection of phages against the most common MDR pathogens. The collection at present contains close to 400 phages that we characterize to select those that are suitable for therapeutic purposes. Roughly half of the phage genomes have been sequenced and analyzed. In this chapter, we describe some of the practical issues related to this project read more ...
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