Molecular Interactions Between Arboviruses and Insect Vectors: Insects' Immune Responses to Virus Infection
Natapong Jupatanakul and George Dimopoulos
from: Arboviruses: Molecular Biology, Evolution and Control (Edited by: Nikos Vasilakis and Duane J. Gubler). Caister Academic Press, U.K. (2016) Pages: 107-118.
Despite the efficient spread of arboviral diseases, the mosquito represents a bottleneck in the transmission of pathogenic viruses. Within the mosquito, arboviruses have to overcome several barriers, imposed by the mosquito innate immune system, microbiota and other factors, to reach the salivary glands from where they can be transmitted to a new host. Here we will address the molecular interactions between viruses and mosquito vectors with emphasis on the innate immune system and microbiota, and discuss their potential for the development of disease control strategies read more ...