Caister Academic Press

CIMB Abstract

Curr. Issues Mol. Biol. (2014) 16: 9-14.

Toxin-antitoxin Systems: Classification, Biological Function and Application in Biotechnology

Sobhan Ghafourian, Mohammad Raftari, Nourkhoda Sadeghifard and Zamberi Sekawi

The toxin-antitoxin (TA) systems are systems in which an unstable antitoxin inhibits a stable toxin. This review aims to introduce the TA system and its biological application in bacteria. For this purpose, first we introduce a new classification for the TA systems based on how the antitoxin can neutralize the toxin, we then describe the functions of TA systems and finally review the application of these systems in biotechnology.

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