biochip

biochip

 

DNA microarrays

DNA microarray is a multiplex technology used in molecular biology, medicine and bioscience. A microarray an arrayed series of thousands of microscopic spots of DNA on a small piece of glass or silicon. These are commonly known as gene chips, biochips or "lab on a chip".

A new two-volume book "Lab-on-a-Chip Technology" was published recently. The book describes the recent innovations in the microarray field and the applications in the fields of medicine, molecular biology, biotechnology and bioscience.

Lab-on-a-Chip Technology: Biomolecular Separation and Analysis ISBN: 978-1-904455-47-9
Lab-on-a-Chip Technology: Fabrication and Microfluidics ISBN: 978-1-904455-46-2

CURRENT BOOKS OF INTEREST
Metagenomics: Theory, Methods and Applications
Aspergillus: Molecular Biology and Genomics
Environmental Molecular Microbiology
Neisseria: Molecular Mechanisms of Pathogenesis
Frontiers in Dengue Virus Research
ABC Transporters in Microorganisms
Pili and Flagella
Lab-on-a-Chip Technology: Biomolecular Separation and Analysis
Lab-on-a-Chip Technology: Fabrication and Microfluidics
Bacterial Polysaccharides
Microbial Toxins
Acanthamoeba
Bacterial Secreted Proteins
Lactobacillus
Mycobacterium
Real-Time PCR
Clostridia
Plant Pathogenic Bacteria
Biopolymers
Plasmids
Pasteurellaceae
Vibrio cholerae
Pathogenic Fungi
Helicobacter pylori
Corynebacteria
Staphylococcus
Leishmania
Archaea
Legionella
RNA and the Regulation of Gene Expression
Molecular Oral Microbiology

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What is Lab on a Chip?

The term 'laboratory' can be defined as a facility which provides controlled conditions for scientific research, experiments or measurements. In recent years, many lab-on-a-chip (LOC) devices, which provide controlled conditions for scientific measurements without a formal laboratory, have been developed and used in a wide array of biomedical and other analytical settings. LOC devices integrate and scale down laboratory functions and processes to a miniaturized chip format. In this context the term 'chip' is used loosely, unlike the 'traditional' silicon chip from electronics. LOC devices, or chips, can be fabricated from many types of material including various polymers (e.g. acrylic, polyester, and polycarbonate), glass, or silicon, as well as combinations of these materials (Herold and Rasooly 2009. Lab-on-a-Chip Technology. Caister Academic Press ISBN: 978-1-904455-47-9).

In this context the term 'chip' is used loosely, unlike the 'traditional' silicon chip from electronics. LOC devices, or chips, can be fabricated from many types of material including various polymers (e.g. acrylic, polyester, and polycarbonate), glass, or silicon, as well as combinations of these materials. Unlike the 'traditional' silicon integrated circuit (IC) fabrication technologies, a broad variety of fabrication technologies are used for LOC device fabrication.

Bibliography:
  1. Lab-on-a-Chip Technology: Fabrication and Microfluidics
  2. Lab-on-a-Chip Technology: Biomolecular Separation and Analysis

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