MicroRNAs
Conference update
April 4 - 5, 2011 Eighth International RNAi, MicroRNAs and Oligos Meeting 2011
Waltham, MA, USA Further information
Meeting on RNA interference: Biochemistry to Drugs and Therapeutics
Suggested reading: RNA Interference and Viruses: Current Innovations and Future Trends
April 4 - 5, 2011 First International Single (Molecule) Cell Biology and Real-Time PCR Meeting 2011
Waltham, MA, USA Further information
Meeting‚ on Single Molecule Detection to Amplification and Molecular Imaging
Suggested reading: Real-Time PCR books
July 11 - 12, 2011 Fourth International Epigenomics, Sequencing and SNiPs Meeting 2011
Boston, MA, USA Further information
Meeting on Chromatin Methylation to Disease Biology and Theranostics
Suggested reading: Epigenetics
Waltham, MA, USA Further information
Meeting on RNA interference: Biochemistry to Drugs and Therapeutics
Suggested reading: RNA Interference and Viruses: Current Innovations and Future Trends
April 4 - 5, 2011 First International Single (Molecule) Cell Biology and Real-Time PCR Meeting 2011
Waltham, MA, USA Further information
Meeting‚ on Single Molecule Detection to Amplification and Molecular Imaging
Suggested reading: Real-Time PCR books
July 11 - 12, 2011 Fourth International Epigenomics, Sequencing and SNiPs Meeting 2011
Boston, MA, USA Further information
Meeting on Chromatin Methylation to Disease Biology and Theranostics
Suggested reading: Epigenetics
Human Alpha-herpesvirus MicroRNAs
Category: Regulation | Virology
from Jennifer L. Umbach and Bryan R. Cullen writing in Alphaherpesviruses: Molecular Virology:
MicroRNAs (miRNAs) are an extensive class of approx 22 nucleotide long regulatory RNAs expressed by all mammalian cells and also by several DNA viruses, including many members of the herpesvirus family. Using deep sequencing technology, it has now been demonstrated that Herpes Simplex Virus 1 (HSV-1) encodes at least eight viral miRNAs, seven of which are expressed in latently infected human neurons. Similarly, HSV-2 has also been shown to encode at least six miRNAs, four of which are evolutionarily conserved between HSV-2 and HSV-1. Perhaps surprisingly, varicella zoster virus does not appear to express any viral miRNAs in latently infected cells. A recent review discusses the potential functions of the currently known HSV-1 and HSV-2 miRNAs, focusing on a possible role in stabilizing viral latency in infected neurons.
Further reading: Alphaherpesviruses: Molecular Virology
MicroRNAs (miRNAs) are an extensive class of approx 22 nucleotide long regulatory RNAs expressed by all mammalian cells and also by several DNA viruses, including many members of the herpesvirus family. Using deep sequencing technology, it has now been demonstrated that Herpes Simplex Virus 1 (HSV-1) encodes at least eight viral miRNAs, seven of which are expressed in latently infected human neurons. Similarly, HSV-2 has also been shown to encode at least six miRNAs, four of which are evolutionarily conserved between HSV-2 and HSV-1. Perhaps surprisingly, varicella zoster virus does not appear to express any viral miRNAs in latently infected cells. A recent review discusses the potential functions of the currently known HSV-1 and HSV-2 miRNAs, focusing on a possible role in stabilizing viral latency in infected neurons.
Further reading: Alphaherpesviruses: Molecular Virology
MicroRNAs Conference
November 1 - 2, 2010 MicroRNAs: Biology to Development and Disease
Oxford, UK Further information
Fifth International MicroRNAs Europe 2010‚ Meeting
Suggested reading: RNA and the Regulation of Gene Expression: A Hidden Layer of Complexity
Oxford, UK Further information
Fifth International MicroRNAs Europe 2010‚ Meeting
Suggested reading: RNA and the Regulation of Gene Expression: A Hidden Layer of Complexity