Biosensors

A biosensor is a compact analytical device or unit incorporating a biological or biologically derived sensitive recognition element integrated or associated with a physio-chemical transducer. Since the first biosensor was developed many new biosensors have been studied and the range of applications extended.

Molecular recognition is central to biosensing. Initially, biosensor recognition elements were isolated from living systems. However, many biosensor recognition elements now available are not naturally occurring but have been synthesized in the laboratory. The sensing of targets, i.e. analytes of interest, is being influenced by the availability of new engineered binding proteins. Employing the techniques of modern biotechnology, it is now possible to construct DNA polynucleotides at will, thus opening new possibilities for the generation of biosensor recognition elements arising from paths not taken by nature.

In the future, the ability to "recognize" and "detect" electrically and magnetically will be radically transformed. The emergence of magnetoelectronics is a promising new platform technology for biorecognition element/sensor development.

from Chambers et al. in Curr. Issues Mol. Biol. (2008) 10: 1-12
abstract     full article pdf

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