Caister Academic Press

Molecular Diagnostics: Current Technology and Applications

Publisher: Horizon Bioscience
Edited by: Juluri R. Rao, Colin C. Fleming and John E. Moore
Queen's University of Belfast, Northern Ireland; Department of Agriculture and Rural Development, Northern Ireland; and Belfast City Hospital, Northern Ireland
Foreword: Professor T Hugh Pennington President of the Society for General Microbiology Read the Foreword
Publication date: August 2006
ISBN-10: 1-904933-19-X
ISBN-13: 978-1-904933-19-9
Pages: x + 380

       

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Molecular techniques are being harnessed for the detection of organisms in a wide range of circumstances. Global trade has introduced new pests of crops and plants; simultaneously, there is universal concern from disease outbreaks such as BSE, Foot & Mouth and the dreaded bird-flu virus. Molecular diagnostic applications for the detection of foodborne bacterial pathogens and genetically modified organisms in food are also becoming increasingly important.

This book provides a critical assessment of the various molecular methods in medical and veterinary science, forensics, biodefense, plant science, food safety and quarantine sciences. Aimed at a wide range of end-users encompassing postgraduates, postdoctoral research scientists, established researchers and specialist scientists, the authors describe and evaluate molecular techniques and applications in this increasingly important area.

Topics include the molecular methods for the direct detection of pathogens such as E. coli O157:H7, MRSA and other important bacterial infections, medical viruses, medical parasites, dental plaque bacteria and haematological malignancies. Also covered is the molecular recognition and detection of catastrophic bio-threat agents as a consequence of global terrorism.

Reviews:

"Science delivers. Molecular Diagnostics: Current Technology and Applications illustrates this in an excellent fashion; how fast, sensitive and specific diagnostic tools address problems in the real world. Its strength is not only that its account is state-of-the-art, but is in its breadth, ranging from plant pathogens, food borne pathogens, GMCs and human pathogens in general to entomology and to bioterrorism." from Hugh Pennington
Professor Pennington is President of the Society for General Microbiology, a Fellow of the Royal Society of Edinburgh and a Fellow of the Academy of Medical Sciences.

"... well written with informative introductory sections ... The book covers the whole gamut of molecular techniques ... from standard PCR through real-time PCR to microarrays and biosensor technology." from Microbiology Today (2006)

"... a selective survey of modern approaches" from Doodys (2007)

Chapter List:

SECTION 1. Applications to Plant and Animal Health

Chapter 1
Update on Molecular Tools for Detection of Plant Pathogenic Bacteria and Viruses
María M. López, Edson Bertolini, Ester Marco-Noales, Pablo Llop and Mariano Cambra

Chapter 2
Molecular Diagnostic Tools for Detection of Plant Pathogenic Fungi
Rosie E. Bradshaw, Simon J. Foster and Brendon J. Monahan

Chapter 3
Application of Molecular Techniques for Detection of Bacterial Veterinary Pathogens
M. Murakami, T. Sekizuka and M. Matsuda

SECTION 2. Applications to Food Safety (Foodborne Pathogens, Pests, GMO)

Chapter 4
Molecular Diagnostics and Epidemiological Typing Methods for Common Foodborne Pathogens Campylobacter and Salmonella
Majella Maher, Sinead Lahiff and Dearbháile Morris

Chapter 5
DNA Biosensor Chips for GMO Detection
Maria Minunni

Chapter 6
Molecular Techniques for Identification of Quarantine Insects and Mites: The Potential of Microarrays
Juerg E. Frey and Monika Pfunder

SECTION 3. Applications to Biomedical and Clinical Sciences

Chapter 7
Biosensor Applications of Peptide Nucleic Acid for Direct Detection of PCR Amplified DNA of Pathogens E. coli 0157:H7 and MRSA
Tomohiko Nishino, Mifumi Shimomura-Shimizu and Isao Karube

Chapter 8
Molecular Diagnostics of Medically Important Bacterial Infections
Beverley Cherie Millar, Jiru Xu and John Edmund Moore

Chapter 9
Molecular Diagnostic Tools for the Detection of Bacteria in Dental Plaque
Wilson A. Coulter, Charles E. Shelburne and Denis E. Lopatin

Chapter 10
Molecular Investigations of Haematological Malignancies
H. Denis Alexander and Mark A. Catherwood

Chapter 11
Molecular Diagnosis of Medical Viruses
Rodney M. Ratcliff, Grace Chang, Tuck Weng Kok and Theo P. Sloots

Chapter 12
Molecular Diagnosis of Parasites of Medical Importance
Lihua Xiao

SECTION 4. Applications to Biothreats, Drugs and Forensics

Chapter 13
Applications of Biosensor Technology for Molecular Recognition and Detection
James P. Chambers

Chapter 14
Molecular Diagnosis and Bioterrorism: An Update
James Dooley and Colm Lowery

How to buy this book

(EAN: 9781904933199)